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Regenerative Research · Reviewed 16 June 2026
Buy Kisspeptin
Also known as Kisspeptin-10, KP-10, Metastin (45-54), KISS1, GPR54/KISS1R Agonist, Metastin C-Terminal Decapeptide
Kisspeptin-10 is the C-terminal decapeptide of the KISS1 gene product that activates KISS1R (GPR54) on hypothalamic GnRH neurons, the master upstream trigger of the reproductive (HPG) axis.
From $125 per 10-vial research pack · 10 × 5 mg · in stock
Single vials from $32 , added to a pack order.
For laboratory and research use only — not for human or veterinary use. 21+.
Inside New-U Research Compounds
Kisspeptin at a glance
What is Kisspeptin?
Kisspeptin-10 is the ten-amino-acid business end of the KISS1 gene product - the single most potent natural trigger of the reproductive hormone axis, acting one step upstream of GnRH itself.
What Kisspeptin research examines
Summarised from published preclinical and clinical literature; findings describe study models, not uses of the research material.
Kisspeptin price and pack sizes
All packs are >99% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.
Current Kisspeptin certificate
The current published certificate for Kisspeptin is an independent Janoshik Analytical report dated 25 August 2026.
Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.
Mechanism summary
Kisspeptin binds KISS1R (GPR54) on GnRH neurons, triggering GnRH release that cascades down to LH, FSH and gonadal sex steroids - the master upstream control point of the reproductive axis.
Evidence summary
Evidence base: Mixed (human + animal)
Kisspeptin has genuine human data - a randomised clinical trial plus human genetic and neuroendocrine challenge studies of the reproductive axis - but no approved indication in any jurisdiction, so the evidence spans clinical-grade endpoints and mechanistic research.
Human studies
Buying Kisspeptin: ordering and delivery
Explore Kisspeptin research
Published research, analytical evidence and comparisons for this compound. Research use only.
Frequently asked questions
Where can I buy Kisspeptin?
Kisspeptin (also known as Kisspeptin-10) is available directly from New-U Research Compounds at https://new-u.io/peptide/kisspeptin. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).
How much does Kisspeptin cost?
Kisspeptin starts at $125 for a 10-vial research pack (5mg per vial) at New-U Research Compounds, with 4 pack sizes listed; single vials from $32 ship as an add-on to a pack order. Orders over $350 ship free.
Is New-U Kisspeptin third-party tested?
Yes. Released Kisspeptin batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Janoshik Analytical, 25 August 2026) reports 99.527% purity and is published at https://new-u.io/coa/kisspeptin.
How fast does Kisspeptin ship, and do you ship internationally?
Kisspeptin ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.
Is it legal to buy Kisspeptin?
In the United States, Kisspeptin is not approved by the FDA for human consumption and is not sold for that purpose. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.
What is Kisspeptin used for in research?
Kisspeptin-10 is the C-terminal decapeptide of the KISS1 gene product that activates KISS1R (GPR54) on hypothalamic GnRH neurons, the master upstream trigger of the reproductive (HPG) axis. New-U supplies Kisspeptin as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Kisspeptin research profile.
What is the typical Kisspeptin research dosage?
Reconstitution volumes and dosing reported in the literature for Kisspeptin are described in research-model terms only. New-U Research Compounds supplies Kisspeptin strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.
What do I use to reconstitute Kisspeptin?
Lyophilised Kisspeptin is reconstituted with bacteriostatic water - sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide.
Can I buy Kisspeptin online and how fast does it ship?
Yes. Kisspeptin can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.
Can I buy Kisspeptin in bulk?
Kisspeptin ships in 10-vial research packs as standard, in 4 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.
What should I look for when choosing where to buy Kisspeptin?
For research-grade Kisspeptin, verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/kisspeptin, and the current Kisspeptin certificate is at https://new-u.io/coa/kisspeptin.
What is kisspeptin and how does it work?
Kisspeptin-10 is the active C-terminal decapeptide of the KISS1 gene product (metastin). It works by binding KISS1R (GPR54), a Gq/11-coupled receptor on hypothalamic GnRH neurons, triggering phospholipase-C signalling and a calcium rise that makes those neurons fire and release GnRH. That GnRH pulse then drives pituitary LH and FSH secretion, placing kisspeptin at the very top of the reproductive hormone cascade.
How is kisspeptin different from a GnRH agonist?
A GnRH agonist acts directly on the pituitary side of the cascade. Kisspeptin acts one step earlier, on the GnRH neurons in the hypothalamus that release GnRH in the first place. That upstream position is why researchers use it to study the natural, physiological control of the reproductive axis rather than overriding it.
What does the human research actually show?
Controlled human physiology studies report that exogenous kisspeptin raises circulating LH (mean increase ~2.75 IU/L in one trial) and, more modestly, FSH, without altering downstream estradiol, progesterone or testosterone over short study windows. Randomised clinical trials in men and women with hypoactive sexual desire disorder also found that kisspeptin modulated activity in sexual-processing brain networks. These are published research findings, not human-use claims - kisspeptin is supplied for laboratory research only.
What is the difference between kisspeptin-10 and kisspeptin-54?
Kisspeptin-54 (metastin) is the full-length peptide; kisspeptin-10 is its C-terminal ten-amino-acid fragment. Both bind the same KISS1R receptor through the shared C-terminal sequence. Kisspeptin-10 is shorter and shorter-acting (a circulating half-life on the order of minutes), while kisspeptin-54 circulates longer, which is why studies pick one or the other depending on whether they need a brief pulse or sustained exposure.
Why is kisspeptin also called metastin?
The KISS1 gene was originally discovered as a metastasis-suppressor gene, and its product was named metastin before the reproductive role of its receptor (GPR54/KISS1R) was understood. Kisspeptin and metastin refer to the same molecule.
How does kisspeptin compare with hCG as a reproductive-axis tool?
They act at opposite ends of the same axis. Kisspeptin acts at the top, on hypothalamic GnRH neurons, recruiting the body's own LH/FSH release in a physiological way. hCG acts at the bottom, directly on the gonad via the LH/CG receptor, mimicking the LH surge. Researchers choose kisspeptin to study upstream, natural control and hCG to drive direct gonadal stimulation.
How should kisspeptin be stored and handled?
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1–6 °C and protect from light. As with most research peptides, avoid repeated freeze-thaw cycles of the reconstituted solution. This is laboratory handling guidance only.
Research references
Independent literature and reference sources for Kisspeptin. Provided for scientific context - New-U Research Compounds supplies research-use-only material.
Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Kisspeptin research profile. Every compound profile is listed in the research peptide index.
PRECISION. PURITY. PERFORMANCE.
Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.
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Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.
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[image: New-U Research Compounds logo and research peptide vial — Buy Kisspeptin at New-U Research Compounds]
[image: Kisspeptin research peptide vial — Hormone / Fertility compound, >99% HPLC]