Shop by goal

  • Metabolic Research
  • GH-Axis Research
  • Muscle & IGF Research
  • Tissue and Cellular Models
  • Regenerative Research
  • Cellular Senescence Research
  • Cognitive Research
  • Multi-Compound Blends
  • Accessories
  • All compounds →

    • Popular compounds

  • BPC-157
  • TB-500
  • GHK-Cu
  • GLP1-RC-RT
  • GLP1-RC-SM
  • Ipamorelin
  • All bestsellers →

    • Research resources

  • Research Glossary
  • Peptide Guides
  • Delivery Guide
  • Track Order

    • Recently viewed

  • Peptide 101
  • Research Areas
  • Peptide Blog
  • Community Forum
  • Crypto Blog
  • Research Glossary
  • Reconstitution Calculator
  • Peptide Tracker
  • Research Protocol Tools
  • Peptide Guides
  • Sign In
  • Create Account
  • Track My Order
  • Refer a Friend
  • My Account
  • My Orders
  • My Referrals
  • Log Out
    • How-to guides
    New-U Research Compounds — Buy Tirzepatide at New-U Research Compounds. Laboratory research use only.

    Metabolic Research · Reviewed 14 August 2026

    Tirzepatide Research

    GLP1-RC-TZ Laboratory Research Material

    Also known as GIP/GLP-1 Dual Agonist, Dual Incretin Agonist, Twincretin

    Tirzepatide is a dual GIP / GLP-1 receptor agonist characterised in published research, with imbalanced agonism favouring GIPR. GLP1-RC-TZ is the New-U catalogue identifier for the analytically verified laboratory research material supplied here.

    From $168 per 10-vial research pack · 10 × 5 mg · in stock

    Single vials from $50 , added to a pack order.

  • View full research profile
  • Compare all 20 formats
  • Certificate of Analysis

    • For laboratory and research use only — not for human or veterinary use. 21+.

    Inside New-U Research Compounds

    Tirzepatide at a glance

    Catalogue identifier
    GLP1-RC-TZ (“Tirz”)
    Compound class
    GIPR / GLP-1R dual-agonist research compound
    Sequence
    YAib-EGTFTSDYSI-Aib-LDKIAQK(C20-diacid-γGlu-AEEA-AEEA)-AFVQWLIAGGPSSGAPPPS-NH2
    Molecular weight
    4,813.53 Da
    Purity
    >99% HPLC
    Form
    Lyophilised powder
    Formats
    10-vial research packs and single vials · 5–120 mg per vial
    Latest certificate
    Janoshik Analytical, 27 May 2026 — 99.899% purity
    Laboratory storage
    Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    GLP1-RC-TZ Research Material

    GLP1-RC-TZ is New-U’s catalogue identifier for the laboratory research material offered through this page.

    Published Tirzepatide research discussed below relates to external investigational studies and their study materials and protocols.

    GLP1-RC-TZ is not offered as a medicine, treatment or therapeutic product and is not intended for human or veterinary use.

    What is Tirzepatide?

    Tirzepatide (LY3298176) is a dual GIP / GLP-1 receptor agonist characterised in published clinical research and approved as a medicine in some jurisdictions under other manufacturers’ brand names.

    GLP1-RC-TZ is a GIPR / GLP-1R dual-agonist research compound, commonly referred to as “Tirz” in research communities.

    Tirzepatide price and pack sizes

    Strength per vial Format Price Cost per mg 5 mg 10-vial research pack $168 $3.36 5 mg Single vial $50 $10.00 10 mg 10-vial research pack $184 $1.84 10 mg Single vial $55 $5.50 15 mg 10-vial research pack $194 $1.29 15 mg Single vial $58 $3.87 20 mg 10-vial research pack $205 $1.02 20 mg Single vial $61 $3.05 30 mg 10-vial research pack $231 $0.77 30 mg Single vial $65 $2.17 40 mg 10-vial research pack $267 $0.67 40 mg Single vial $67 $1.68 50 mg 10-vial research pack $314 $0.63 50 mg Single vial $74 $1.48 60 mg 10-vial research pack $338 $0.56 60 mg Single vial $84 $1.40 100 mg 10-vial research pack $526 $0.53 100 mg Single vial $156 $1.56 120 mg 10-vial research pack · out of stock $550 $0.46 120 mg Single vial · out of stock $165 $1.38

    All packs are >99% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.

    Current Tirzepatide certificate

    The current published certificate for GLP1-RC-TZ research material is an independent Janoshik Analytical report dated 27 May 2026.

    Laboratory Janoshik Analytical Report date 27 May 2026 Purity 99.899% Report number 164666 Earlier certificates on file 1
  • View the Tirzepatide certificate and testing history
  • Download the report (PDF)
  • How to read a Certificate of Analysis

    • Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Mechanism summary

    Published experimental work characterises dual GIPR / GLP-1R agonist activity with imbalanced agonism, plus an albumin-binding structural modification investigated as a contributor to prolonged systemic exposure.

    Target or pathway Reported activity Research significance GIPR Full agonist activity characterised experimentally, comparable to native GIP The arm that distinguishes the dual agonist from single GLP-1R compounds in the literature GLP-1R Agonist activity characterised as biased, favouring cAMP signalling over β-arrestin recruitment Investigated in relation to receptor desensitisation over prolonged exposure Adipose GIPR signalling Direct GIPR-mediated adipose effects characterised experimentally Investigated as a contributor to measured insulin-sensitivity markers and adiponectin Albumin-binding modification C20 eicosanedioic acid via a γGlu/AEEA spacer; 99% plasma protein binding reported Investigated as a contributor to prolonged systemic exposure (~5-day apparent half-life) Proteolytic stability Aib2 and Aib13 substitutions Structural modifications investigated for altered peptide stability against DPP-IV and proteases

    Pharmacokinetics at a glance

    Half-life Apparent elimination half-life reported at approximately 5 days (mean 116.7 h); steady-state exposure reported after ~4 weeks Metabolism Proteolytic backbone cleavage, β-oxidation of the C20 fatty-diacid chain and amide hydrolysis reported; metabolites eliminated ~66% renally / ~33% faecally; no CYP-mediated interactions

    Evidence summary

    Evidence base: Tier 1: Human clinical

    The evidence tier describes the published literature on Tirzepatide, the scientific subject, and specifically on the finished pharmaceutical studied in those trials. Published clinical findings summarised on this page relate to the investigational materials and protocols used in those external studies. They do not establish the safety, efficacy, intended use or clinical equivalence of New-U GLP1-RC-TZ research material.

    Human studies

  • SURMOUNT-1 obesity RCT — −20.9% mean change from baseline in body weight at week 72 (NEJM 2022; PMID 35658024)
  • SURMOUNT-5 head-to-head RCT vs semaglutide — −20.2% vs −13.7% at week 72 (NEJM 2025; PMID 40353578)
  • SURPASS-CVOT cardiovascular-outcomes RCT — 13,000+ participants (NEJM 2025); SURPASS diabetes programme

    • Buying Tirzepatide: ordering and delivery

    Delivery time
    Approximately 6–14 business days worldwide
    Dispatch
    Orders typically dispatch within 48 hours of confirmed payment.
    Ships from
    US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer.
    Shipping cost
    Flat $35 USD worldwide · free over $350 USD
    Payment
    Card, Apple Pay, Google Pay, Cash App, Cryptocurrency
    Packaging
    Discreet packaging
    In transit
    Lyophilised peptides are stable through the tracked transit window.
    Purchasers
    21+ · laboratory research use only

    Explore Tirzepatide research

    Published research, analytical evidence and comparisons for this compound. Research use only.

  • Research guide Tirzepatide research guide Published experimental work characterises dual GIPR / GLP-1R agonist activity with imbalanced agonism, plus an albumin-binding structural… Read the guide →
  • Analytical evidence View the Tirzepatide COA Current batch purity and identity testing, 2026-05-27. View the COA →
  • Compare Compare Tirzepatide and Retatrutide Tirzepatide vs Retatrutide: mechanism, receptor profile and specifications side by side. Compare →
  • Related research Retatrutide vs tirzepatide: triple vs dual agonist, compared Triple (GIP/GLP-1/glucagon) vs dual (GIP/GLP-1) agonism, the Phase 2/3 weight-loss data (24.2% vs 22.5%), regulatory status and side-effect… Read the article →
  • Compare Compare Tirzepatide and Semaglutide Tirzepatide vs Semaglutide: mechanism, receptor profile and specifications side by side. Compare →

    • Frequently asked questions

    Where can I buy Tirzepatide?

    Tirzepatide (also known as GIP/GLP-1 Dual Agonist) is available directly from New-U Research Compounds at https://new-u.io/peptide/tirzepatide. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).

    How much does Tirzepatide cost?

    Tirzepatide starts at $168 for a 10-vial research pack (5mg per vial) at New-U Research Compounds, with 20 pack sizes listed; single vials from $50 ship as an add-on to a pack order. Orders over $350 ship free.

    Is New-U Tirzepatide third-party tested?

    Yes. Released Tirzepatide batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Janoshik Analytical, 27 May 2026) reports 99.899% purity and is published at https://new-u.io/coa/tirzepatide.

    How fast does Tirzepatide ship, and do you ship internationally?

    Tirzepatide ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.

    Is it legal to buy Tirzepatide?

    GLP1-RC-TZ is supplied strictly as laboratory research material and is not offered for human or veterinary use. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.

    What is Tirzepatide used for in research?

    Tirzepatide is a dual GIP / GLP-1 receptor agonist characterised in published research, with imbalanced agonism favouring GIPR. GLP1-RC-TZ is the New-U catalogue identifier for the analytically verified laboratory research material supplied here. New-U supplies Tirzepatide as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Tirzepatide research profile.

    What analytical documentation is available for GLP1-RC-TZ?

    Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Each published certificate records the independent laboratory, report number, RP-HPLC purity result, mass-spectrometry identity confirmation and test date; the current GLP1-RC-TZ certificate is at https://new-u.io/coa/tirzepatide, so you can check it before you order. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Does published Tirzepatide clinical research apply to GLP1-RC-TZ?

    No. Published clinical findings summarised on this page relate to the investigational materials and protocols used in those external studies. They do not establish the safety, efficacy, intended use or clinical equivalence of New-U GLP1-RC-TZ research material. The two evidence types are kept separate on this page for that reason: batch analysis is New-U's own analytical work on the supplied lot, and the trial data is external work on the investigational or approved material those studies used.

    Can I buy Tirzepatide online and how fast does it ship?

    Yes. Tirzepatide can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.

    Can I buy Tirzepatide in bulk?

    Tirzepatide ships in 10-vial research packs as standard, in 20 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy Tirzepatide?

    For research-grade Tirzepatide, verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/tirzepatide, and the current Tirzepatide certificate is at https://new-u.io/coa/tirzepatide.

    What is Tirzepatide in scientific research?

    Tirzepatide (LY3298176) is a 39-amino-acid synthetic peptide characterised in receptor-pharmacology studies as a dual GIP / GLP-1 receptor agonist with imbalanced agonism. It is approved as a medicine in some jurisdictions under other manufacturers' brand names; the material supplied here is not that finished pharmaceutical.

    What is GLP1-RC-TZ?

    GLP1-RC-TZ is New-U's catalogue identifier for the laboratory research material offered through this research profile. It is not a medicine, a treatment, a generic pharmaceutical or a therapeutic product, it is not equivalent to any clinical or commercial product, and it is not offered for human or veterinary use.

    Which receptor systems are examined in Tirzepatide research?

    Published in-vitro pharmacology characterises two receptors: GIPR, where agonist potency is reported as comparable to native GIP, and GLP-1R, where signalling is reported as biased toward cAMP generation over β-arrestin recruitment. Structural work additionally investigates the C20 fatty-diacid albumin-binding modification and the Aib2/Aib13 substitutions for altered proteolytic stability.

    What analytical testing accompanies GLP1-RC-TZ?

    Each released GLP1-RC-TZ batch is tested by an independent analytical laboratory for purity by RP-HPLC area normalisation and for identity by mass spectrometry, and the result is published as a batch-linked Certificate of Analysis recording the laboratory, report number, measured purity and test date. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Where can I view the current batch COA for GLP1-RC-TZ?

    The current batch certificate — laboratory, report number, measured purity and test date — is published at /coa/tirzepatide, together with the testing history for the compound.

    What does >99% HPLC purity mean?

    It is a purity figure obtained by reversed-phase high-performance liquid chromatography using area normalisation: the target peak accounts for more than 99% of the total integrated peak area in the chromatogram for the tested sample. It is a statement about chemical purity of that sample only, and says nothing about sterility, endotoxin content, pharmaceutical equivalence or any clinical property.

    What clinical trials are referenced on this page?

    Three external studies of the reference medicine: SURMOUNT-1 (Jastreboff et al., NEJM 2022; PMID 35658024), SURMOUNT-5 (Aronne et al., NEJM 2025; PMID 40353578) and SURPASS-CVOT (NEJM 2025; DOI 10.1056/NEJMoa2505928), alongside the receptor-pharmacology characterisation in JCI Insight (2020). Each reported result on this page is attributed to its study, arm and timepoint.

    How is published clinical research distinguished from New-U batch testing?

    They are separate bodies of evidence. Published clinical research is external work on the approved finished pharmaceutical, conducted under those studies' own protocols; it establishes nothing about the material supplied here. New-U batch testing is analytical work on the GLP1-RC-TZ lot itself — RP-HPLC purity and mass-spectrometry identity — and it establishes nothing clinical. A certificate of analysis combined with an external clinical paper does not amount to clinical validation of GLP1-RC-TZ.

    Is GLP1-RC-TZ the same as an approved branded medicine?

    No. Approved branded tirzepatide products are prescription, sterile finished pharmaceuticals manufactured under cGMP by their marketing authorisation holder. GLP1-RC-TZ is unapproved laboratory research material supplied as a lyophilised powder. It is not equivalent to, a generic of, or a substitute for any approved product.

    Why is Tirzepatide described as imbalanced in the literature?

    Because the two receptor arms are not matched: published pharmacology reports full agonist potency at GIPR comparable to native GIP, but biased signalling at GLP-1R that favours cAMP generation over β-arrestin recruitment. The literature investigates that asymmetry in relation to receptor desensitisation over prolonged exposure.

    How does Tirzepatide research differ from Retatrutide and Semaglutide research?

    By receptor coverage as characterised in the literature: semaglutide research describes GLP-1R agonism, tirzepatide research describes GIPR/GLP-1R agonism, and retatrutide research investigates GLP-1R/GIPR/GCGR agonism. Only SURMOUNT-5 was designed as a head-to-head comparison (tirzepatide vs semaglutide); results drawn from separate programmes are not head-to-head comparisons.

    What form is GLP1-RC-TZ supplied in?

    GLP1-RC-TZ is supplied as a lyophilised powder in sealed vials, in sealed 10-vial research packs across the listed strengths; the batch-linked Certificate of Analysis is published on the product page.

    How should laboratory research material be stored?

    Store the lyophilised powder in a freezer at −20 °C. If a laboratory protocol requires the material in solution, hold the resulting solution refrigerated at 1–6 °C, protected from light, and avoid repeated freeze–thaw cycles, which can degrade the fatty-acid modification. Storage conditions are laboratory handling information only.

    Research references

    Independent literature and reference sources for Tirzepatide. Provided for scientific context - New-U Research Compounds supplies research-use-only material.

  • Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). N Engl J Med.
  • Aronne LJ et al. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5). N Engl J Med.
  • SURPASS-CVOT: Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes. N Engl J Med.

    • Looking for receptor pharmacology, pharmacokinetics, registered clinical research and references? See the full Tirzepatide research profile. Every compound profile is listed in the research peptide index.

    Part of the Metabolic & GLP-1 research research area — explore related compounds, guides and sources.

    PRECISION. PURITY. PERFORMANCE.

    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

    Shop

  • All research compounds
  • Price list
  • Where to buy peptides
  • Compare compounds
  • Compare vial sizes
  • Affiliate programme

    • Research

  • Peptide 101
  • Published COAs
  • Research areas
  • Research blog
  • How-to guides
  • Peptide guides
  • Research glossary

    • Support

  • Track your order
  • Contact us
  • Shipping & delivery
  • International shipping
  • FAQ
  • Community forum
  • Refund policy

    • Ways to Pay

  • Google Pay
  • Apple Pay
  • Venmo
  • Cryptocurrency
  • Crypto wallets
  • Cash App
  • Card payments
  • Bank transfer (SEPA)
  • Paying with crypto
  • Live crypto prices

    • Shop by goal

  • Metabolic Research
  • GH-Axis Research
  • Muscle & IGF Research
  • Tissue and Cellular Models
  • Regenerative Research
  • Cellular Senescence Research
  • Cognitive Research
  • Multi-Compound Blends
  • Accessories

    • Shop by compound

  • BPC-157
  • TB-500
  • GHK-Cu
  • Tesamorelin
  • Retatrutide
  • Semaglutide
  • Tirzepatide
  • CJC-1295 (without DAC)
  • All compounds →

    • Shop by region

  • United Kingdom
  • United States
  • Australia
  • Canada
  • Canada (FR)
  • Ireland
  • Northern Ireland
  • Malta
  • Germany
  • France
  • Spain
  • Italy
  • Netherlands
  • Portugal
  • Greece
  • Austria
  • Poland
  • Sweden
  • Finland
  • Denmark
  • Norway
  • Croatia
  • Slovakia
  • Slovenia
  • Estonia
  • Latvia
  • Lithuania
  • Czechia
  • Hungary
  • Romania
  • Bulgaria
  • Belgium
  • Belgium (FR)
  • Luxembourg
  • Deutsch
  • Ελληνικά
  • Español
  • Français
  • Italiano

    • Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.

    All rights reserved. Copyright of New-U held with Hilxera Distribution Services LLC 2026.

    Website & business operated by Hilxera Distribution Services LLC. Registered in Wyoming, ID: 2026-001928701.

    Principal office: 1712 Pioneer Ave., Ste. 500, Cheyenne, WY 82001, USA

    © 2026 New-U Research Compounds · new-u.io

    [image: New-U Research Compounds logo and research peptide vial — Buy Tirzepatide at New-U Research Compounds]

    [image: Tirzepatide research peptide vial — Metabolic Research compound, >99% HPLC]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

    © 2026 New-U Research Compounds · new-u.io — Copyright held with Hilxera Distribution Services LLC. All rights reserved.