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Metabolic & GLP-1 research

The incretin and metabolic research area - GLP-1, GIP and glucagon receptor agonists studied in obesity and metabolic science.

Incretin research is one of the most active areas in modern metabolic science. GLP-1 receptor agonists - and the newer dual (GLP-1/GIP) and triple (GLP-1/GIP/glucagon) agonists - are studied for their effects on energy balance, insulin sensitivity and body-weight regulation in preclinical and clinical literature.

This hub groups the research compounds New-U supplies in this area alongside the on-site guides that summarise the published science.

All 5 compounds in this area have a current published Certificate of Analysis from an independent laboratory, linked on its card below and listed at /coa.

Research compounds in this area

Research reading

glp 1 rc comparison

retatrutide phase 3 trials triumph

is retatrutide safe

oral vs injectable glp1

cagrisema cagrilintide research guide

beyond glp 1 next obesity research wave

Explore Metabolic & GLP-1 research

Per-compound research guides, side-by-side comparisons and current analytical evidence for the compounds studied in this area. Research use only.

Research guide Retatrutide research guide Published experimental work characterises agonist activity across GLP-1R, GIPR and GCGR, with structural modifications investigated for… Read the guide →

Research guide Tirzepatide research guide Published experimental work characterises dual GIPR / GLP-1R agonist activity with imbalanced agonism, plus an albumin-binding structural… Read the guide →

Research guide Semaglutide research guide Published experimental work characterises GLP-1R agonist activity, with an albumin-binding structural modification investigated as a… Read the guide →

Research guide Cagrilintide research guide Cagrilintide activates all three amylin receptor subtypes plus the calcitonin receptor, modulating arcuate nucleus appetite neurons and… Read the guide →

Research guide Eloralintide research guide Eloralintide is a selective amylin receptor agonist that preferentially activates AMY1R to engage satiety circuits and reduce food intake -… Read the guide →

Compare Compare Retatrutide and Semaglutide Retatrutide vs Semaglutide: mechanism, receptor profile and specifications side by side. Compare →

Compare Compare Tirzepatide and Retatrutide Tirzepatide vs Retatrutide: mechanism, receptor profile and specifications side by side. Compare →

Compare Compare Tirzepatide and Semaglutide Tirzepatide vs Semaglutide: mechanism, receptor profile and specifications side by side. Compare →

Compare Compare Retatrutide and Liraglutide Retatrutide vs Liraglutide: mechanism, receptor profile and specifications side by side. Compare →

Frequently asked questions

What are GLP-1 receptor agonists in a research context?

GLP-1 (glucagon-like peptide-1) receptor agonists are peptides that bind the GLP-1 receptor, a target studied in metabolic and obesity research for its role in glucose-dependent insulin secretion and energy balance. New-U supplies these compounds for laboratory research use only.

What is the difference between single, dual and triple agonists?

Single agonists (e.g. semaglutide) target the GLP-1 receptor; dual agonists add GIP-receptor activity; triple agonists (e.g. retatrutide) add glucagon-receptor activity. The multi-receptor compounds are a newer focus of published metabolic research.

How is purity verified?

Released batches are analysed by independent laboratories (Janoshik Analytical and Freedom Diagnostics) by RP-HPLC for purity and mass spectrometry for identity. Every released sale batch must pass independent verification before it is offered for sale. Published Certificates of Analysis are listed per compound at /coa. In this area, all 5 compounds have a current published certificate.

Scientific sources & further reading

GLP-1 receptor agonist - Wikipedia

Semaglutide - Wikipedia

Retatrutide - Wikipedia

Research use only - all claims made on this site are for testing and research use only. This page summarises published research context and does not constitute medical advice or dosing guidance.

PRECISION. PURITY. PERFORMANCE.

Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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