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    New-U Research Compounds — Buy Retatrutide at New-U Research Compounds. Laboratory research use only.

    Metabolic Research · Reviewed 14 August 2026

    Retatrutide Research

    GLP1-RC-RT Laboratory Research Material

    Also known as GGG Triple Agonist, GLP-1/GIP/Glucagon Receptor Triple Agonist, Tri-Agonist

    Retatrutide (LY3437943) is an investigational triple GLP-1R / GIPR / GCGR agonist evaluated in registered clinical research. GLP1-RC-RT is the New-U catalogue identifier for the analytically verified laboratory research material supplied here.

    From $210 per 10-vial research pack · 10 × 5 mg · in stock

    Single vials from $53 , added to a pack order.

  • View full research profile
  • Compare all 16 formats
  • Certificate of Analysis
  • For laboratory and research use only — not for human or veterinary use. 21+.

    Inside New-U Research Compounds

    Retatrutide at a glance

    Catalogue identifier
    GLP1-RC-RT (“Reta”)
    Compound class
    Triple GLP-1R / GIPR / GCGR agonist research compound
    Sequence
    YAib-QGTFTSDYSIL(αMe)-LDKK(C20-diacid-γGlu-AEEA)-AQAAib-FIEYLLEGGPSSGAPPPS(amide)
    Molecular weight
    4,894.6 Da
    Purity
    >99% HPLC
    Form
    Lyophilised powder
    Formats
    10-vial research packs and single vials · 5–60 mg per vial
    Latest certificate
    Janoshik Analytical, 24 July 2026 — 99.556% purity
    Laboratory storage
    Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    GLP1-RC-RT Research Material

    GLP1-RC-RT is New-U’s catalogue identifier for the laboratory research material offered through this page.

    Published Retatrutide research discussed below relates to external investigational studies and their study materials and protocols.

    GLP1-RC-RT is not offered as a medicine, treatment or therapeutic product and is not intended for human or veterinary use.

    What is Retatrutide?

    Retatrutide (LY3437943) is an investigational triple GLP-1R / GIPR / GCGR agonist being evaluated in registered clinical research. It is not an approved medicine.

    GLP1-RC-RT is a triple GLP-1R / GIPR / GCGR agonist research compound, commonly referred to as “Reta” in research communities.

    Retatrutide price and pack sizes

    Strength per vial Format Price Cost per mg 5 mg 10-vial research pack $210 $4.20 5 mg Single vial $53 $10.60 10 mg 10-vial research pack $252 $2.52 10 mg Single vial $63 $6.30 15 mg 10-vial research pack $299 $1.99 15 mg Single vial $75 $5.00 20 mg 10-vial research pack $347 $1.74 20 mg Single vial $87 $4.35 30 mg 10-vial research pack $441 $1.47 30 mg Single vial $110 $3.67 40 mg 10-vial research pack $546 $1.36 40 mg Single vial $137 $3.42 50 mg 10-vial research pack $599 $1.20 50 mg Single vial $150 $3.00 60 mg 10-vial research pack $630 $1.05 60 mg Single vial $158 $2.63

    All packs are >99% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.

    Current Retatrutide certificate

    The current published certificate for GLP1-RC-RT research material is an independent Janoshik Analytical report dated 24 July 2026.

    Laboratory Janoshik Analytical Report date 24 July 2026 Purity 99.556% Report number 209088 Earlier certificates on file 3
  • View the Retatrutide certificate and testing history
  • Download the report (PDF)
  • How to read a Certificate of Analysis
  • Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Mechanism summary

    Published experimental work characterises agonist activity across GLP-1R, GIPR and GCGR, with structural modifications investigated for proteolytic stability and prolonged systemic exposure.

    Target or pathway Reported activity Research significance GLP-1R Agonist activity characterised in receptor pharmacology studies Reported EC50 0.775 nM; the receptor shared with the single- and dual-agonist reference compounds GIPR Agonist activity characterised experimentally Reported EC50 0.0643 nM; potency reported as 8.9-fold that of native GIP GCGR Agonist activity characterised experimentally Reported EC50 5.79 nM; the arm that distinguishes the triple agonist from dual GLP-1/GIP compounds in the literature Albumin-binding modification C20 fatty diacid via an AEEA-γGlu spacer Investigated as a contributor to prolonged systemic exposure (~6-day apparent half-life) Proteolytic stability Aib2, Aib20 and α-methylleucine-13 substitutions Structural modifications investigated for altered peptide stability against DPP-IV and protease cleavage

    Pharmacokinetics at a glance

    Half-life Apparent elimination half-life reported at approximately 6 days under the investigated protocols; steady-state exposure reported after 3–4 weeks Metabolism Hepatic proteolytic metabolism plus β-oxidation of the C20 fatty-diacid chain reported; no CYP-mediated interactions reported

    Evidence summary

    Evidence base: Tier 1: Human clinical

    The evidence tier describes the published literature on Retatrutide, the scientific subject. Retatrutide remains investigational and is not approved in any jurisdiction. Published clinical findings summarised on this page relate to the investigational materials and protocols used in those external studies. They do not establish the safety, efficacy, intended use or clinical equivalence of New-U GLP1-RC-RT research material.

    Human studies

  • TRIUMPH-1 pivotal Phase 3 obesity RCT — −28.3% mean change from baseline in body weight at week 80 (NCT05929066; sponsor-reported topline, ADA 2026; not yet peer-reviewed)
  • Triple-agonist Phase 2 obesity RCT — −24.2% mean change from baseline at week 48 (NEJM 2023; PMID 37385275)
  • Phase 2a MASLD trial — up to 82.4% relative hepatic fat-fraction reduction (Nat Med 2024)
  • Buying Retatrutide: ordering and delivery

    Delivery time
    Approximately 6–14 business days worldwide
    Dispatch
    Orders typically dispatch within 48 hours of confirmed payment.
    Ships from
    US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer.
    Shipping cost
    Flat $35 USD worldwide · free over $350 USD
    Payment
    Card, Apple Pay, Google Pay, Cash App, Cryptocurrency
    Packaging
    Discreet packaging
    In transit
    Lyophilised peptides are stable through the tracked transit window.
    Purchasers
    21+ · laboratory research use only

    Explore Retatrutide research

    Published research, analytical evidence and comparisons for this compound. Research use only.

  • Research guide Retatrutide research guide Published experimental work characterises agonist activity across GLP-1R, GIPR and GCGR, with structural modifications investigated for… Read the guide →
  • Analytical evidence View the Retatrutide COA Current batch purity and identity testing, 2026-07-24. View the COA →
  • Compare Compare Retatrutide and Semaglutide Retatrutide vs Semaglutide: mechanism, receptor profile and specifications side by side. Compare →
  • Related research Is Retatrutide Safe? What the Research and the Safety Warnings Actually Show After 2026 news reports of retatrutide ("reta") being sold online despite its unapproved status, what the research actually shows on… Read the article →
  • Compare Compare Retatrutide and Tirzepatide Retatrutide vs Tirzepatide: mechanism, receptor profile and specifications side by side. Compare →
  • Frequently asked questions

    Where can I buy Retatrutide?

    Retatrutide (also known as GGG Triple Agonist) is available directly from New-U Research Compounds at https://new-u.io/peptide/retatrutide. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).

    How much does Retatrutide cost?

    Retatrutide starts at $210 for a 10-vial research pack (5mg per vial) at New-U Research Compounds, with 16 pack sizes listed; single vials from $53 ship as an add-on to a pack order. Orders over $350 ship free.

    Is New-U Retatrutide third-party tested?

    Yes. Released Retatrutide batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Janoshik Analytical, 24 July 2026) reports 99.556% purity and is published at https://new-u.io/coa/retatrutide.

    How fast does Retatrutide ship, and do you ship internationally?

    Retatrutide ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.

    Is it legal to buy Retatrutide?

    GLP1-RC-RT is supplied strictly as laboratory research material and is not offered for human or veterinary use. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.

    What is Retatrutide used for in research?

    Retatrutide (LY3437943) is an investigational triple GLP-1R / GIPR / GCGR agonist evaluated in registered clinical research. GLP1-RC-RT is the New-U catalogue identifier for the analytically verified laboratory research material supplied here. New-U supplies Retatrutide as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Retatrutide research profile.

    What analytical documentation is available for GLP1-RC-RT?

    Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Each published certificate records the independent laboratory, report number, RP-HPLC purity result, mass-spectrometry identity confirmation and test date; the current GLP1-RC-RT certificate is at https://new-u.io/coa/retatrutide, so you can check it before you order. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Does published Retatrutide clinical research apply to GLP1-RC-RT?

    No. Published clinical findings summarised on this page relate to the investigational materials and protocols used in those external studies. They do not establish the safety, efficacy, intended use or clinical equivalence of New-U GLP1-RC-RT research material. The two evidence types are kept separate on this page for that reason: batch analysis is New-U's own analytical work on the supplied lot, and the trial data is external work on the investigational or approved material those studies used.

    Can I buy Retatrutide online and how fast does it ship?

    Yes. Retatrutide can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.

    Can I buy Retatrutide in bulk?

    Retatrutide ships in 10-vial research packs as standard, in 16 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy Retatrutide?

    For research-grade Retatrutide, verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/retatrutide, and the current Retatrutide certificate is at https://new-u.io/coa/retatrutide.

    What is GLP1-RC-RT?

    GLP1-RC-RT is New-U's catalogue designation for this analytically verified research compound, commonly referred to as “Reta” within research communities. It is supplied as laboratory research material: not a medicine, a treatment, a generic pharmaceutical or a therapeutic product, not equivalent to any clinical or commercial product, and not offered for human or veterinary use.

    Which receptor systems have been investigated?

    Published in-vitro pharmacology characterises agonist activity at three receptors: GLP-1R (reported EC50 0.775 nM), GIPR (reported EC50 0.0643 nM, with potency reported as 8.9-fold that of native GIP) and GCGR (reported EC50 5.79 nM). Structural work additionally investigates the C20 fatty-diacid albumin-binding modification as a contributor to prolonged systemic exposure, and Aib/α-methylleucine substitutions for altered proteolytic stability.

    What analytical testing accompanies GLP1-RC-RT?

    Each released GLP1-RC-RT batch is tested by an independent analytical laboratory (Janoshik Analytical or Freedom Diagnostics) for purity by RP-HPLC area normalisation and for identity by mass spectrometry, and the result is published as a batch-linked Certificate of Analysis recording the laboratory, report number, measured purity and test date. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Where can I view the current batch COA for GLP1-RC-RT?

    The current batch certificate — laboratory, report number, measured purity and test date — is published at /coa/retatrutide, together with the testing history for the compound. It is readable before ordering rather than on request afterwards.

    What does >99% HPLC purity mean?

    It is a purity figure obtained by reversed-phase high-performance liquid chromatography using area normalisation: the target peak accounts for more than 99% of the total integrated peak area in the chromatogram for the tested sample. It is a statement about chemical purity of that sample only. It does not describe sterility, endotoxin content, heavy-metal content, pharmaceutical equivalence or any clinical property.

    What clinical trials are referenced on this page?

    Three external studies of the investigational compound: the randomised Phase 2 obesity trial (Jastreboff et al., N Engl J Med 2023; PMID 37385275, DOI 10.1056/NEJMoa2301972), the Phase 2a MASLD trial (Sanyal et al., Nat Med 2024; DOI 10.1038/s41591-024-03018-2) and the Phase 3 TRIUMPH-1 trial (ClinicalTrials.gov NCT05929066). Each reported result on this page is attributed to its study, arm and timepoint. TRIUMPH-1 figures are sponsor-reported topline presented at ADA 2026 and have not yet been peer-reviewed; the Phase 2 and Phase 2a figures come from peer-reviewed journal publications.

    How is published clinical research distinguished from New-U batch testing?

    They are separate bodies of evidence and this page keeps them apart. Published clinical research is external work on Retatrutide as an investigational compound, using those studies' own materials and protocols; it establishes nothing about the material supplied here. New-U batch testing is analytical work on the GLP1-RC-RT lot itself — RP-HPLC purity and mass-spectrometry identity — and it establishes nothing clinical. A certificate of analysis combined with an external clinical paper does not amount to clinical validation of GLP1-RC-RT.

    What form is GLP1-RC-RT supplied in?

    GLP1-RC-RT is supplied as a lyophilised powder in sealed vials, in single-vial laboratory samples and sealed 10-vial research packs across the listed strengths; the batch-linked Certificate of Analysis is published on the product page.

    How should laboratory research material be stored?

    Store the lyophilised powder in a freezer at −20 °C. If a laboratory protocol requires the material in solution, hold the resulting solution refrigerated at 1–6 °C, protected from light, and avoid repeated freeze–thaw cycles, which can degrade the fatty-acid modification. Storage conditions are laboratory handling information only.

    How does this receptor profile differ from the dual and single agonists?

    The three classes are distinguished by receptor coverage: the semaglutide literature describes GLP-1R agonism, the tirzepatide literature describes GIPR/GLP-1R agonism, and this compound is investigated for GLP-1R/GIPR/GCGR agonism. Their clinical programmes were conducted separately, so published results from one programme are not head-to-head comparisons with another.

    Is GLP1-RC-RT an approved medicine?

    No. The associated compound is investigational and is being evaluated in registered clinical studies; it is not approved in any jurisdiction. The material supplied here is laboratory research material and is not offered as a medicine, therapeutic product, or material for human or veterinary use.

    Research references

    Independent literature and reference sources for Retatrutide. Provided for scientific context - New-U Research Compounds supplies research-use-only material.

  • Jastreboff AM et al. Triple–Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med.
  • Sanyal AJ et al. Triple hormone receptor agonist retatrutide for MASLD: a randomized phase 2a trial. Nat Med.
  • TRIUMPH-1: A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight - Phase 3 (Pivotal). ClinicalTrials.gov trial registration record.
  • Eli Lilly and Company. Lilly’s triple agonist, retatrutide, delivered powerful weight loss in pivotal Phase 3 obesity trial. Sponsor announcement (topline; not peer-reviewed), presented at ADA 86th Scientific Sessions.
  • Katsi V, Koutsopoulos G, Fragoulis C, Dimitriadis K, Tsioufis K. Retatrutide - A Game Changer in Obesity Pharmacotherapy. Biomolecules (review).
  • Looking for receptor pharmacology, pharmacokinetics, registered clinical research and references? See the full Retatrutide research profile. Every compound profile is listed in the research peptide index.

    Part of the Metabolic & GLP-1 research research area — explore related compounds, guides and sources.

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    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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  • Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.

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    [image: Retatrutide research peptide vial — Metabolic Research compound, >99% HPLC]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

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