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  • How-to guides
    New-U Research Compounds — Buy Cagrilintide at New-U Research Compounds. Laboratory research use only.

    Metabolic Research · Reviewed 16 June 2026

    Buy Cagrilintide

    Also known as Cagrilintide Acetate, Long-Acting Amylin Analogue, Amylin Analogue Research Peptide

    From $263 per 10-vial research pack · 10 × 5 mg · in stock

    Single vials from $42 , added to a pack order.

  • View full research profile
  • Compare all 4 formats
  • Certificate of Analysis
  • For laboratory and research use only — not for human or veterinary use. 21+.

    Inside New-U Research Compounds

    Cagrilintide at a glance

    Sequence
    {C20-diacid-γGlu}-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2
    Molecular weight
    4,409.01 Da
    Pathways studied
    AMY1R / AMY2R / AMY3R · Calcitonin receptor (CTR) · Arcuate NPY/POMC neurons · Glucagon suppression
    Purity
    >99% HPLC
    Form
    Lyophilised powder
    Formats
    10-vial research packs and single vials · 5–10 mg per vial
    Latest certificate
    Janoshik Analytical, 25 August 2026 — 99.945% purity
    Laboratory storage
    Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    What is Cagrilintide?

    What Cagrilintide research examines

  • Non-selective AMYR/CTR agonist activating all three amylin receptor subtypes and calcitonin receptor
  • Anti-fibrillation design: 25P/28P/29P substitutions prevent amyloid β-sheet aggregation
  • Suppresses glucagon secretion and delays gastric emptying complementary to GLP-1 receptor agonism
  • Additive mechanism with GLP-1 RAs through distinct and overlapping neural satiety circuits
  • Summarised from published preclinical and clinical literature; findings describe study models, not uses of the research material.

    Cagrilintide price and pack sizes

    Strength per vial Format Price Cost per mg 5 mg 10-vial research pack $263 $5.26 5 mg Single vial $42 $8.40 10 mg 10-vial research pack $347 $3.47 10 mg Single vial $63 $6.30

    All packs are >99% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.

    Current Cagrilintide certificate

    The current published certificate for Cagrilintide is an independent Janoshik Analytical report dated 25 August 2026.

    Laboratory Janoshik Analytical Report date 25 August 2026 Purity 99.945% Report number 224333
  • View the Cagrilintide certificate and testing history
  • Download the report (PDF)
  • How to read a Certificate of Analysis
  • Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Mechanism summary

    Target or pathway Reported activity Research significance Calcitonin receptor (CTR) C-terminal Pro→Tyr substitution increases CTR potency Adds a parallel signalling arm beyond classic amylin receptors Glucagon suppression Lowers postprandial glucagon secretion Reduces hepatic glucose output, complementary to GLP-1 Gastric emptying Delays gastric emptying Prolongs satiety and flattens postprandial glucose excursion

    Pharmacokinetics at a glance

    Metabolism Proteolytic cleavage of the peptide backbone plus β-oxidation of the C20 fatty-diacid chain

    Evidence summary

    Evidence base: Tier 1: Human clinical

    Buying Cagrilintide: ordering and delivery

    Delivery time
    Approximately 6–14 business days worldwide
    Dispatch
    Orders typically dispatch within 48 hours of confirmed payment.
    Ships from
    US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer.
    Shipping cost
    Flat $35 USD worldwide · free over $350 USD
    Payment
    Card, Apple Pay, Google Pay, Cash App, Cryptocurrency
    Packaging
    Discreet packaging
    In transit
    Lyophilised peptides are stable through the tracked transit window.
    Purchasers
    21+ · laboratory research use only

    Explore Cagrilintide research

    Published research, analytical evidence and comparisons for this compound. Research use only.

  • Research guide Cagrilintide research guide Cagrilintide activates all three amylin receptor subtypes plus the calcitonin receptor, modulating arcuate nucleus appetite neurons and… Read the guide →
  • Analytical evidence View the Cagrilintide COA Current batch purity and identity testing, 2026-08-25. View the COA →
  • Related research CagriSema & Cagrilintide: The Amylin + GLP-1 Combo Explained Novo Nordisk's combination of cagrilintide (an amylin analogue) and semaglutide (a GLP-1 agonist) - the mechanism, the REDEFINE Phase 3… Read the article →
  • Related research Retatrutide vs cagrilintide: triple agonist vs amylin analogue, compared A GIP/GLP-1/glucagon triple agonist against a long-acting amylin analogue: why they are not like-for-like alternatives, what REDEFINE 1… Read the article →
  • Frequently asked questions

    Where can I buy Cagrilintide?

    Cagrilintide (also known as Cagrilintide Acetate) is available directly from New-U Research Compounds at https://new-u.io/peptide/cagrilintide. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).

    How much does Cagrilintide cost?

    Cagrilintide starts at $263 for a 10-vial research pack (5mg per vial) at New-U Research Compounds, with 4 pack sizes listed; single vials from $42 ship as an add-on to a pack order. Orders over $350 ship free.

    Is New-U Cagrilintide third-party tested?

    Yes. Released Cagrilintide batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Janoshik Analytical, 25 August 2026) reports 99.945% purity and is published at https://new-u.io/coa/cagrilintide.

    How fast does Cagrilintide ship, and do you ship internationally?

    Cagrilintide ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.

    Is it legal to buy Cagrilintide?

    In the United States, Cagrilintide is not approved by the FDA for human consumption and is not sold for that purpose. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.

    What is the typical Cagrilintide research dosage?

    Reconstitution volumes and dosing reported in the literature for Cagrilintide are described in research-model terms only. New-U Research Compounds supplies Cagrilintide strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

    What do I use to reconstitute Cagrilintide?

    Lyophilised Cagrilintide is reconstituted with bacteriostatic water - sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide.

    Can I buy Cagrilintide online and how fast does it ship?

    Yes. Cagrilintide can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.

    Can I buy Cagrilintide in bulk?

    Cagrilintide ships in 10-vial research packs as standard, in 4 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy Cagrilintide?

    For research-grade Cagrilintide, verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/cagrilintide, and the current Cagrilintide certificate is at https://new-u.io/coa/cagrilintide.

    What is cagrilintide and how does it work?

    Cagrilintide (AM833) is a long-acting, acylated analogue of the pancreatic hormone amylin. It is a non-selective agonist of the three amylin receptor subtypes (AMY1/2/3R) plus the calcitonin receptor, and acts on arcuate-nucleus appetite neurons to suppress hunger while delaying gastric emptying and lowering postprandial glucagon. A C20 fatty-diacid anchor binds serum albumin to extend its half-life to roughly eight days, supporting once-weekly research dosing.

    How is cagrilintide different from a GLP-1 agonist?

    GLP-1 agonists activate the GLP-1 receptor. Cagrilintide activates the amylin receptor family (AMY1/2/3R) plus the calcitonin receptor. The two pathways engage different appetite circuits, which is why combining them (as in CagriSema research) produces larger effects than either alone.

    What does the research on cagrilintide actually show?

    A Phase 2 dose-finding trial (Lancet 2021) reported dose-dependent body-weight reduction with cagrilintide monotherapy. In the Phase 3 REDEFINE 1 trial (NEJM 2025), the cagrilintide + semaglutide combination (CagriSema) reported a 20.4% mean reduction versus 3.0% placebo at 68 weeks on the treatment-policy estimand, with cagrilintide alone around 11.5% and semaglutide alone around 14.9%. These are descriptive clinical-trial findings, not outcomes promised for any use of this research-grade material.

    Cagrilintide vs semaglutide - what is the difference?

    They act through entirely different hormone systems: semaglutide is a GLP-1 receptor agonist, while cagrilintide is an amylin/calcitonin-receptor agonist. Their half-lives are similar (cagrilintide ~159–195 h, semaglutide ~145–165 h), both supporting once-weekly dosing. In the REDEFINE programme the two were studied together precisely because their satiety pathways are additive rather than redundant.

    What side effects were observed in cagrilintide studies?

    The most frequently reported events in published trials were gastrointestinal - nausea, vomiting, decreased appetite, constipation or diarrhoea - that were typically mild-to-moderate, escalation-related and transient, plus injection-site reactions. Gallbladder events have been noted in combination research. These are observations recorded in the clinical literature, not a safety profile for any human use of this research material.

    Why is the anti-fibrillation design important?

    Native human amylin forms amyloid fibrils that are toxic to pancreatic islet cells and make the peptide impractical for sustained research use. Substituting prolines at positions 25, 28, and 29 (borrowed from rat amylin, which does not aggregate) blocks the fibrillation pathway.

    How is cagrilintide reconstituted and stored?

    Keep the lyophilised powder at −20 °C in the freezer. Reconstitute with bacteriostatic water by directing it down the vial wall rather than onto the powder, then swirl gently - do not shake. After reconstitution, refrigerate at 1–6 °C and protect from light. Avoid repeated freeze-thaw cycles, which can damage the fatty-acid tail.

    Is cagrilintide approved or legal?

    Cagrilintide is an investigational compound and is not an approved medicine on its own; the CagriSema combination remains in late-phase clinical development. The material supplied here is unapproved, research-grade laboratory material sold strictly for in-vitro and preclinical research use only - not for human use.

    What happens if you stop taking peptides?

    It depends on the peptide class. Cagrilintide is a long-acting amylin analogue studied for appetite and metabolic research, often alongside GLP-1 peptides. As with the GLP-1 class, the research literature on appetite-regulating peptides indicates the appetite effects depend on continued receptor stimulation, so they wane once administration stops and the compound clears; cagrilintide's long half-life means that clearance is gradual. These observations come from research and clinical studies; cagrilintide here is an unapproved research-grade peptide.

    Research references

    Independent literature and reference sources for Cagrilintide. Provided for scientific context - New-U Research Compounds supplies research-use-only material.

  • Cagrilintide — Wikipedia
  • Lau DCW et al. Once-weekly cagrilintide for weight management: a phase 2, dose-finding trial. Lancet.
  • REDEFINE 1: Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity. N Engl J Med.
  • Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Cagrilintide research profile. Every compound profile is listed in the research peptide index.

    Part of the Metabolic & GLP-1 research research area — explore related compounds, guides and sources.

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    © 2026 New-U Research Compounds · new-u.io

    [image: New-U Research Compounds logo and research peptide vial — Buy Cagrilintide at New-U Research Compounds]

    [image: Cagrilintide research peptide vial — Metabolic Research compound, >99% HPLC]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

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