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Growth hormone secretagogue research

The GH-axis research area - GHRH analogues and ghrelin-receptor agonists studied for their effect on pulsatile growth-hormone secretion.

Growth-hormone secretagogue research studies two complementary peptide classes: GHRH analogues (sermorelin, CJC-1295, tesamorelin) that act on the growth-hormone-releasing-hormone receptor, and ghrelin-receptor agonists / GHRPs (ipamorelin, GHRP-2, GHRP-6, hexarelin) that act on the GHS-R. The two classes are often studied in combination for their effect on pulsatile GH release in preclinical models.

This hub groups the research compounds New-U supplies in this area alongside the on-site guides that summarise the published science.

3 of the 8 compounds in this area have a current published Certificate of Analysis from an independent laboratory, linked on its card below and listed at /coa.

Research compounds in this area

Research reading

cjc 1295 ipamorelin research guide

ipamorelin vs sermorelin

tesamorelin research guide

tesamorelin vs sermorelin

hexarelin vs ipamorelin

hexarelin vs cjc 1295

hexarelin what the research shows

Explore Growth hormone secretagogue research

Per-compound research guides, side-by-side comparisons and current analytical evidence for the compounds studied in this area. Research use only.

Research guide CJC-1295 (with DAC) research guide CJC-1295 DAC hijacks serum albumin as a carrier, letting a GHRH analog stay in circulation for a week and continuously nudge the pituitary… Read the guide →

Research guide CJC-1295 (without DAC) research guide Mod GRF 1-29 activates the GHRH receptor to produce a short, natural-shaped pulse of growth hormone, synergising with ghrelin-receptor… Read the guide →

Research guide Ipamorelin research guide Ipamorelin is a highly selective ghrelin receptor agonist that triggers GH release on somatotrophs without activating the corticotroph or… Read the guide →

Research guide Sermorelin research guide Sermorelin binds the GHRH receptor on pituitary somatotrophs and triggers a pulse of natural growth hormone, preserving the body's own… Read the guide →

Research guide Tesamorelin research guide Tesamorelin binds the GHRH receptor on pituitary somatotrophs to drive a natural pulse of growth hormone, which then raises IGF-1 and… Read the guide →

Research guide GHRP-2 research guide GHRP-2 activates the ghrelin receptor on pituitary somatotrophs, triggering a sharp GH pulse with modest increases in cortisol and… Read the guide →

Research guide GHRP-6 research guide GHRP-6 activates two receptors simultaneously - the ghrelin receptor GHS-R1a for GH release and appetite, and CD36 for cytoprotective… Read the guide →

Research guide Hexarelin research guide Hexarelin hits two receptors: GHS-R1a on pituitary cells to release growth hormone, and CD36 on heart cells to improve cardiac function - a… Read the guide →

Compare Compare CJC-1295 (with DAC) and CJC-1295 (without DAC) CJC-1295 (with DAC) vs CJC-1295 (without DAC): mechanism, receptor profile and specifications side by side. Compare →

Compare Compare CJC-1295 (with DAC) and Ipamorelin CJC-1295 (with DAC) vs Ipamorelin: mechanism, receptor profile and specifications side by side. Compare →

Compare Compare CJC-1295 (without DAC) and Ipamorelin CJC-1295 (without DAC) vs Ipamorelin: mechanism, receptor profile and specifications side by side. Compare →

Compare Compare Sermorelin and CJC-1295 (with DAC) Sermorelin vs CJC-1295 (with DAC): mechanism, receptor profile and specifications side by side. Compare →

Frequently asked questions

What is a growth hormone secretagogue?

A growth hormone secretagogue is a compound studied for its ability to stimulate the secretion of growth hormone. Research distinguishes GHRH analogues (which act on the GHRH receptor) from ghrelin-receptor agonists / GHRPs (which act on the GHS-R). New-U supplies these compounds for laboratory research use only.

Why are GHRH analogues and GHRPs studied together?

In the published literature the two classes act on different receptors and are frequently studied in combination (e.g. CJC-1295 with ipamorelin) because their mechanisms are complementary in models of pulsatile growth-hormone release.

How is purity verified?

Released batches are analysed by independent laboratories (Janoshik Analytical and Freedom Diagnostics) by RP-HPLC for purity and mass spectrometry for identity. Every released sale batch must pass independent verification before it is offered for sale. Published Certificates of Analysis are listed per compound at /coa. In this area, 3 of the 8 compounds have a current published certificate.

Scientific sources & further reading

Growth hormone secretagogue - Wikipedia

Sermorelin - Wikipedia

Ipamorelin - Wikipedia

Research use only - all claims made on this site are for testing and research use only. This page summarises published research context and does not constitute medical advice or dosing guidance.

PRECISION. PURITY. PERFORMANCE.

Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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