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  • How-to guides
    New-U Research Compounds — Buy CJC-1295 (with DAC) at New-U Research Compounds. Laboratory research use only.

    GH-Axis Research · Reviewed 16 June 2026

    Buy CJC-1295 (with DAC)

    Also known as CJC-1295 with DAC, DAC:GRF, Drug Affinity Complex GRF, CJC-1295 DAC, Modified GRF 1-29 with DAC, ConjuChem GRF

    CJC-1295 DAC, long-acting GHRH analogue with maleimidopropionic acid Drug Affinity Complex enabling covalent albumin binding and 6–8 day half-life.

    From $244 per 10-vial research pack · 10 × 5 mg · in stock

    Single vials from $50 , added to a pack order.

  • View full research profile
  • Compare all 2 formats
  • Certificate of Analysis
  • For laboratory and research use only — not for human or veterinary use. 21+.

    Inside New-U Research Compounds

    CJC-1295 (with DAC) at a glance

    Sequence
    Tyr-DAla-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(MPA)-NH2
    Molecular weight
    3,647.3 Da
    Pathways studied
    GHRH receptor · DAC / albumin conjugation · Tetrasubstitution · Pulsatile GH release
    Purity
    >99% HPLC
    Form
    Lyophilised powder
    Formats
    10-vial research packs and single vials · 5 mg per vial
    Latest certificate
    Freedom Diagnostics, 9 February 2026 — 99.669% purity
    Laboratory storage
    Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    What is CJC-1295 (with DAC)?

    CJC-1295 with DAC is a long-acting GHRH analog that covalently bonds to serum albumin, extending its functional half-life from minutes to roughly 6-8 days for weekly GH research protocols.

    What CJC-1295 (with DAC) research examines

  • Covalent albumin bioconjugation via MPA-Cys34 bond extends half-life to 5.8–8.1 days
  • Tetrasubstituted GHRH(1-29) backbone confers complete DPP-IV protease resistance
  • Elevates IGF-1 levels 1.5–3-fold with accumulative effect over 9–28 days
  • Maintains GHRH receptor-mediated pulsatile GH release pattern preserving somatostatin feedback
  • Summarised from published preclinical and clinical literature; findings describe study models, not uses of the research material.

    CJC-1295 (with DAC) price and pack sizes

    Strength per vial Format Price Cost per mg 5 mg 10-vial research pack $244 $4.88 5 mg Single vial $50 $10.00

    All packs are >99% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.

    Current CJC-1295 (with DAC) certificate

    The current published certificate for CJC-1295 (with DAC) is an independent Freedom Diagnostics report dated 9 February 2026.

    Laboratory Freedom Diagnostics Report date 9 February 2026 Purity 99.669% Report number 2602050112
  • View the CJC-1295 (with DAC) certificate and testing history
  • Download the report (PDF)
  • How to read a Certificate of Analysis
  • Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.

    Mechanism summary

    CJC-1295 DAC hijacks serum albumin as a carrier, letting a GHRH analog stay in circulation for a week and continuously nudge the pituitary to release growth hormone.

    Target or pathway Reported activity Research significance GHRH receptor Full agonist at the pituitary somatotroph GHRHR Triggers cAMP-dependent GH exocytosis like native GHRH DAC / albumin conjugation Covalent bond to serum albumin Cys34 within ~15 min Shields the peptide from degradation and renal clearance for days Tetrasubstitution D-Ala2, Gln8, Ala15, Leu27 block proteases Stops DPP-IV and common oxidation pathways from inactivating the peptide

    Pharmacokinetics at a glance

    Metabolism Gradual proteolytic degradation of the albumin-bound peptide; no CYP-mediated interactions

    Evidence summary

    Evidence base: Mixed (human + animal)

    Human pharmacodynamic and early-phase clinical data exist for the reference compound, but CJC-1295 DAC was never approved. The research-grade material supplied here is unapproved laboratory material.

    Human studies

  • Teichman et al. JCEM 2006 - pharmacodynamic/PK study in 66 healthy adults
  • Animal and laboratory studies

  • Jette et al. Endocrinology 2005 - DAC/albumin-binding chemistry and ~700× half-life extension
  • Buying CJC-1295 (with DAC): ordering and delivery

    Delivery time
    Approximately 6–14 business days worldwide
    Dispatch
    Orders typically dispatch within 48 hours of confirmed payment.
    Ships from
    US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer.
    Shipping cost
    Flat $35 USD worldwide · free over $350 USD
    Payment
    Card, Apple Pay, Google Pay, Cash App, Cryptocurrency
    Packaging
    Discreet packaging
    In transit
    Lyophilised peptides are stable through the tracked transit window.
    Purchasers
    21+ · laboratory research use only

    Explore CJC-1295 (with DAC) research

    Published research, analytical evidence and comparisons for this compound. Research use only.

  • Research guide CJC-1295 (with DAC) research guide CJC-1295 DAC hijacks serum albumin as a carrier, letting a GHRH analog stay in circulation for a week and continuously nudge the pituitary… Read the guide →
  • Analytical evidence View the CJC-1295 (with DAC) COA Current batch purity and identity testing, 2026-02-09. View the COA →
  • Compare Compare CJC-1295 (with DAC) and CJC-1295 (without DAC) CJC-1295 (with DAC) vs CJC-1295 (without DAC): mechanism, receptor profile and specifications side by side. Compare →
  • Related research CJC-1295 & ipamorelin: a research guide to the GHRH + GHRP pair The most-studied GHRH + GHRP research combination. CJC-1295 with DAC vs no-DAC explained, ipamorelin’s selective ghrelin-receptor… Read the article →
  • Compare Compare CJC-1295 (with DAC) and Ipamorelin CJC-1295 (with DAC) vs Ipamorelin: mechanism, receptor profile and specifications side by side. Compare →
  • Frequently asked questions

    Where can I buy CJC-1295 (with DAC)?

    CJC-1295 (with DAC) (also known as CJC-1295 with DAC) is available directly from New-U Research Compounds at https://new-u.io/peptide/cjc-1295-dac. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).

    How much does CJC-1295 (with DAC) cost?

    CJC-1295 (with DAC) starts at $244 for a 10-vial research pack (5mg per vial) at New-U Research Compounds, with 2 pack sizes listed; single vials from $50 ship as an add-on to a pack order. Orders over $350 ship free.

    Is New-U CJC-1295 (with DAC) third-party tested?

    Yes. Released CJC-1295 (with DAC) batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Freedom Diagnostics, 9 February 2026) reports 99.669% purity and is published at https://new-u.io/coa/cjc-1295-dac.

    How fast does CJC-1295 (with DAC) ship, and do you ship internationally?

    CJC-1295 (with DAC) ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.

    Is it legal to buy CJC-1295 (with DAC)?

    In the United States, CJC-1295 (with DAC) is not approved by the FDA for human consumption and is not sold for that purpose. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.

    What is CJC-1295 (with DAC) used for in research?

    CJC-1295 DAC, long-acting GHRH analogue with maleimidopropionic acid Drug Affinity Complex enabling covalent albumin binding and 6–8 day half-life. New-U supplies CJC-1295 (with DAC) as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the CJC-1295 (with DAC) research profile.

    What is the typical CJC-1295 (with DAC) research dosage?

    Reconstitution volumes and dosing reported in the literature for CJC-1295 (with DAC) are described in research-model terms only. New-U Research Compounds supplies CJC-1295 (with DAC) strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

    What do I use to reconstitute CJC-1295 (with DAC)?

    Lyophilised CJC-1295 (with DAC) is reconstituted with bacteriostatic water - sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide.

    Can I buy CJC-1295 (with DAC) online and how fast does it ship?

    Yes. CJC-1295 (with DAC) can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.

    Can I buy CJC-1295 (with DAC) in bulk?

    CJC-1295 (with DAC) ships in 10-vial research packs as standard, in 2 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy CJC-1295 (with DAC)?

    For research-grade CJC-1295 (with DAC), verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/cjc-1295-dac, and the current CJC-1295 (with DAC) certificate is at https://new-u.io/coa/cjc-1295-dac.

    Can I buy CJC-1295 (with DAC) and Ipamorelin together?

    Yes. New-U Research Compounds supplies both CJC-1295 (with DAC) and Ipamorelin as separate research-grade vials. CJC-1295 with DAC and the selective GHSR-1a agonist Ipamorelin are commonly co-studied in growth-hormone-axis research, pairing an extended-half-life GHRH analogue with a ghrelin-mimetic. Order CJC-1295 (with DAC) at https://new-u.io/peptide/cjc-1295-dac and Ipamorelin at https://new-u.io/peptide/ipamorelin.

    What is CJC-1295?

    CJC-1295 is a synthetic analogue of growth-hormone-releasing hormone (GHRH 1-29) with four amino-acid substitutions that resist enzymatic breakdown. It activates the pituitary GHRH receptor to drive growth-hormone release. This DAC version adds a "Drug Affinity Complex" tag that binds serum albumin, extending its half-life to ~6-8 days. Supplied as a lyophilised research-grade powder for laboratory use only.

    What does CJC-1295 do?

    In research models CJC-1295 binds the GHRH receptor on the pituitary and stimulates the release of growth hormone, which in turn raises IGF-1. The DAC tag sustains that signal for days rather than minutes. These are findings in cell and animal models; no human therapeutic effect is implied.

    Is CJC-1295 safe?

    In published animal studies CJC-1295 has generally been well tolerated, but there are no controlled human safety trials, so human safety is not established. It is a research compound, not a medicine; New-U makes no human-use claims and supplies it for laboratory research only.

    Is CJC-1295 FDA approved?

    No. CJC-1295 is an investigational research peptide and is not approved by the FDA, EMA, or any other regulator for human therapeutic use. It is sold strictly for preclinical and in-vitro research.

    What does "DAC" actually mean?

    DAC stands for "Drug Affinity Complex". It is a small chemistry tag - specifically maleimidopropionic acid - attached to the C-terminal lysine of the peptide. When you inject the peptide, the DAC reacts with the free thiol of cysteine-34 on serum albumin, forming a covalent bond. The peptide then piggy-backs on albumin for days.

    How is CJC-1295 DAC different from the no-DAC version?

    Both share the same tetrasubstituted GHRH(1-29) backbone. The DAC version carries the albumin-binding tag and lasts ~6-8 days; the no-DAC version (often called Modified GRF 1-29) has no DAC tag and lasts roughly 30 minutes. DAC is used for sustained elevation; no-DAC is used for physiologic pulses.

    Which is better - CJC-1295 DAC or no-DAC?

    Neither is universally "better" - they answer different research questions. The DAC form gives sustained, days-long GH/IGF-1 elevation from a single dose and is studied on roughly weekly schedules thanks to its 6-8 day half-life. The no-DAC form (Modified GRF 1-29) produces short, natural-shaped GH pulses and is studied with more frequent dosing. The choice depends on whether a study needs continuous elevation or pulsatile signalling. Neither is an approved medicine.

    Why combine CJC-1295 with ipamorelin?

    GHRH analogs like CJC-1295 and ghrelin-receptor agonists like ipamorelin hit two different receptors (GHRHR and GHSR) that synergise in GH release. Combining them produces larger, cleaner GH pulses than either peptide alone, which is why this is a standard research pairing.

    How should CJC-1295 DAC be stored?

    Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The DAC chemistry is relatively stable once the peptide is in solution, but plan dosing to use reconstituted material within the standard peptide-stability window.

    What happens if you stop taking peptides?

    CJC-1295 is a GHRH analogue that stimulates the pituitary's own GH release rather than replacing a hormone. In the research literature, ending administration returns the GH/IGF-1 axis toward its untreated baseline; the DAC form's albumin binding means it clears over a week or more, so the stimulus tapers gradually rather than stopping instantly. Unlike exogenous HGH, no axis-shutdown rebound is described. These are research-model observations.

    Research references

    Independent literature and reference sources for CJC-1295 (with DAC). Provided for scientific context - New-U Research Compounds supplies research-use-only material.

  • CJC-1295 (with DAC) — Wikipedia
  • Teichman SL et al. Prolonged Stimulation of GH and IGF-I Secretion by CJC-1295, a Long-Acting Analog of GH-Releasing Hormone, in Healthy Adults. J Clin Endocrinol Metab.
  • Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full CJC-1295 (with DAC) research profile. Every compound profile is listed in the research peptide index.

    Part of the Growth hormone secretagogue research research area — explore related compounds, guides and sources.

    PRECISION. PURITY. PERFORMANCE.

    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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  • Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.

    All rights reserved. Copyright of New-U held with Hilxera Distribution Services LLC 2026.

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    Principal office: 1712 Pioneer Ave., Ste. 500, Cheyenne, WY 82001, USA

    © 2026 New-U Research Compounds · new-u.io

    [image: New-U Research Compounds logo and research peptide vial — Buy CJC-1295 (with DAC) at New-U Research Compounds]

    [image: CJC-1295 (with DAC) research peptide vial — HGH / Somatropin compound, >99% HPLC]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

    © 2026 New-U Research Compounds · new-u.io — Copyright held with Hilxera Distribution Services LLC. All rights reserved.