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Metabolic Research · Reviewed 16 June 2026
Buy Epitalon
Also known as Epithalon, Epithalone, AEDG Peptide, Ala-Glu-Asp-Gly, Epitalon Tetrapeptide, Khavinson Peptide, Epithalamin Synthetic Analog
Epitalon (also spelled Epithalon) is a four-amino-acid tetrapeptide that reactivates telomerase expression in human somatic cells, extending replicative lifespan beyond the Hayflick limit in classic fibroblast aging experiments.
From $125 per 10-vial research pack · 10 × 10 mg · in stock
Single vials from $35 , added to a pack order.
For laboratory and research use only — not for human or veterinary use. 21+.
Inside New-U Research Compounds
Epitalon at a glance
What is Epitalon?
Epitalon (also spelled Epithalon) is a four-amino-acid tetrapeptide that reactivates telomerase expression in human somatic cells, extending replicative lifespan beyond the Hayflick limit in classic fibroblast aging experiments.
What Epitalon research examines
Summarised from published preclinical and clinical literature; findings describe study models, not uses of the research material.
Epitalon price and pack sizes
All packs are 98.7% HPLC research-grade material. Cost per mg is the price divided by the total mg in the pack. Single vials ship only as an add-on to an order that includes a 10-vial research pack. Flat $35 USD worldwide · free over $350 USD.
Current Epitalon certificate
The current published certificate for Epitalon is an independent Janoshik Analytical report dated 27 May 2026.
Certificates of Analysis are published on the website — on each product page and at /coa — rather than packed with orders. Batch analysis reports identity and purity for the sample tested. It does not establish sterility, endotoxin or heavy-metal status, pharmaceutical equivalence, or any clinical property.
Mechanism summary
Epitalon binds specific DNA motifs and histone proteins in the hTERT promoter region, switching on telomerase expression and allowing telomeres to lengthen in cells that had turned the enzyme off.
Evidence summary
Evidence base: Mixed (human + animal)
Epitalon's best-documented mechanism data are in-vitro - hTERT reactivation and telomere elongation in human cell culture (Khavinson et al., Bull Exp Biol Med, 2003; PMID 12937682). Animal work reports pineal melatonin restoration, and human data are limited to small longevity studies of variable rigor, much of which concerns the related pineal extract epithalamin rather than the synthetic AEDG tetrapeptide. Epitalon has no Western regulatory approval and is supplied as unapproved laboratory material.
Human studies
Animal and laboratory studies
Buying Epitalon: ordering and delivery
Explore Epitalon research
Published research, analytical evidence and comparisons for this compound. Research use only.
Frequently asked questions
Where can I buy Epitalon?
Epitalon (also known as Epithalon) is available directly from New-U Research Compounds at https://new-u.io/peptide/epitalon. It is supplied as lyophilised research-grade material; every released sale batch is independently verified by Janoshik Analytical and Freedom Diagnostics before it is offered for sale, and orders ship direct from source worldwide (approximately 6–14 business days).
How much does Epitalon cost?
Epitalon starts at $125 for a 10-vial research pack (10mg per vial) at New-U Research Compounds, with 4 pack sizes listed; single vials from $35 ship as an add-on to a pack order. Orders over $350 ship free.
Is New-U Epitalon third-party tested?
Yes. Released Epitalon batches are verified by independent laboratories (Janoshik Analytical and Freedom Diagnostics) for identity and purity before they are offered for sale. The current published certificate (Janoshik Analytical, 27 May 2026) reports 98.748% purity and is published at https://new-u.io/coa/epitalon.
How fast does Epitalon ship, and do you ship internationally?
Epitalon ships discreetly and tracked worldwide. US orders ship from the USA or China depending on stock and fulfilment; all other destinations ship from China, direct from the manufacturer. Delivery takes approximately 6–14 business days worldwide. Shipping is free on orders over $350. Card and cryptocurrency payments are accepted.
Is it legal to buy Epitalon?
In the United States, Epitalon is not approved by the FDA for human consumption and is not sold for that purpose. Research use only - all claims made on this site are for testing and research use only. Regulatory requirements vary by product, intended use and jurisdiction. Purchasers are responsible for ensuring that acquisition and use of research material complies with applicable requirements.
What is Epitalon used for in research?
Epitalon (also spelled Epithalon) is a four-amino-acid tetrapeptide that reactivates telomerase expression in human somatic cells, extending replicative lifespan beyond the Hayflick limit in classic fibroblast aging experiments. New-U supplies Epitalon as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Epitalon research profile.
What is the typical Epitalon research dosage?
Reconstitution volumes and dosing reported in the literature for Epitalon are described in research-model terms only. New-U Research Compounds supplies Epitalon strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.
What do I use to reconstitute Epitalon?
Lyophilised Epitalon is reconstituted with bacteriostatic water - sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide.
Can I buy Epitalon online and how fast does it ship?
Yes. Epitalon can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $350.
Can I buy Epitalon in bulk?
Epitalon ships in 10-vial research packs as standard, in 4 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $350. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.
What should I look for when choosing where to buy Epitalon?
For research-grade Epitalon, verify four things: (1) independent third-party purity testing with a published Certificate of Analysis - New-U uses Janoshik Analytical and Freedom Diagnostics; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/epitalon, and the current Epitalon certificate is at https://new-u.io/coa/epitalon.
Is "Epitalon" the same as "Epithalon"?
Yes - the two spellings refer to the same tetrapeptide (Ala-Glu-Asp-Gly). "Epitalon" and "Epithalon" are interchangeable transliterations of the Russian name. You will also see "Epithalone" and "AEDG peptide" in the literature, all referring to the same compound.
How does Epitalon activate telomerase?
Epitalon binds specific DNA motifs (the ATTTC element) in the hTERT promoter and forms complexes with histone proteins, which favours transcription of hTERT - the catalytic subunit of telomerase. Re-expressing hTERT in somatic cells that had silenced it lets telomeres lengthen rather than shorten with each division. This is a promoter-level mechanism rather than indirect signalling, which is unusual for such a small peptide.
Does Epitalon actually extend lifespan in humans?
That is a longevity research question that has not been definitively answered. The cell-culture telomere-elongation data is clear, and there are animal studies showing increased maximum lifespan. Human longevity data is limited to small studies and the related pineal extract epithalamin, not the synthetic AEDG peptide. It remains a research compound, not a validated longevity therapy.
What dosing pattern appears in the published protocols?
Published Russian research protocols describe a pulsed pattern - around 5-10 mg subcutaneously once daily for 10-20 consecutive days, followed by a 4-6 month rest period before the next cycle. This pulse-then-rest design mirrors the original animal study schedules. These figures are descriptive of the literature and are not a recommendation; the material is for laboratory research only.
How is Epitalon different from FOXO4-DRI?
Both are studied in aging research but work on opposite ends of the problem. Epitalon is a telomerase activator that aims to slow telomere-driven senescence by keeping cells dividing, whereas FOXO4-DRI is a senolytic that selectively kills cells that have already become senescent. One delays the onset of senescence; the other clears existing "zombie" cells.
How should Epitalon be stored?
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The tetrapeptide is small and simple, so it tolerates standard peptide handling well within the normal usage window.
Research references
Independent literature and reference sources for Epitalon. Provided for scientific context - New-U Research Compounds supplies research-use-only material.
Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Epitalon research profile. Every compound profile is listed in the research peptide index.
Part of the Cognitive & longevity research research area — explore related compounds, guides and sources.
PRECISION. PURITY. PERFORMANCE.
Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.
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Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.
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[image: New-U Research Compounds logo and research peptide vial — Buy Epitalon at New-U Research Compounds]
[image: Epitalon research peptide vial — Metabolic / Longevity compound, 98.7% HPLC]